EnglishFrançais

Ce site a été mis à jour le 14 mars 2017

Women’s health, Breast Cancer, Smoking - No. 700 Imprimer
Cigarette Smoking and the Incidence of Breast Cancer
Fei Xue, et al ( Arch Intern Med. 2011;171(2):125-133. doi:10.1001/archinternmed.2010.503) evaluated the effect of smoking on breast cancer (BC) incidence in the prospective cohort study of 111 140 participants of the Nurses' Health Study from 1976 to 2006 for active smoking and 36 017 women from 1982 to 2006 for passive smoking. During 3 005 863 person-years of follow-up, 8772 incident cases of invasive BC were reported. After adjustment for potential confounders, the HR of BC was 1.06% (95%CI, 1.01%-1.10%) for ever smokers relative to never smokers. Breast cancer incidence was associated with a higher quantity of current (P for trend = .02) and past (P for trend = .003) smoking, younger age at smoking initiation (P for trend = .01), longer duration of smoking (P for trend = .01), and more pack-years of smoking (P for trend = .005). Premenopausal smoking was associated with a slightly higher incidence of BC (HR, 1.11; 95% CI, 1.07-1.15 for every increase of 20 pack-years), especially smoking before first birth (1.18; 1.10-1.27 for every increase of 20 pack-years). Conversely, the direction of the association between postmenopausal smoking and BC was inverse (0.93; 0.85-1.02 for every increase of 20 pack-years). Passive smoking in childhood or adulthood was not associated with BC risk.
Conclusion Active smoking, especially smoking before the first birth, may be associated with a modest increase in the risk of BC.
 
Сделайте правильный выбор! Онлайн или реальные слоты? Играйте на реальные деньги!
займ онлайн